A Seventh-day Adventist Organization

Curriculum - Clinical Laboratory Science

Program Curriculum

Course Didactic Schedule - Junior year

  Summer     
  5 weeks
  Fall
  10 weeks
  Winter    
  10 weeks
 Spring 
 10 weeks
Orientation

CLSM 321 (4)
Hematology I

CLSM 322 (4)
Hematology II
CLSM 303 (1)
Urine and Body Fluid Analysis
CLSM 309 (4)
Quanatative Analysis
CLSM 331 (5)
Biochemistry
CLSM 332 (4)
Clinical Chemistry I     
CLSM 333 (4)
Clinical Chemistry II
CLSM 105 (4)
Procedures in Phlebotomy
CLSM 307 (3)
Medical Parasitology   
CLSM 327 (5)
Clinical and Pathogenic   
Microbiology I
CLSM 328 (5)
Clinical and Pathogenic
Microbiology II
  CLSM 325  (3)
Clinical Immunology
CLSM 341 (3)
Immunohematology I
CLSM 342 (3)
Immunohematology II
  AHCJ 418 (4)
Physiology
AHCJ 328
Wholeness Portfolio
CLSM 396 (2)
Junior Seminar
  AHCJ 328
Wholeness Portfolio
  AHCJ 328
Wholeness Portfolio I

**A microscope rental fee per quarter is required in the preclinical curriculum. A laboratory breakage fee will be assessed at the end of the junior year.

CLSM 105 Procedures in Phlebotomy (4)
Training in venipuncture and skin puncture, medical terminology, laboratory safety, CPR, basic anatomy and physiology, specimen-collection techniques, hazards/complications, quality assurance methods, and medico legal issues of phlebotomy.  Clinical rotation arranged at Loma Linda University Medical Center.  CPR training and certificate arranged for students not already certified.

AHCJ 328  Wholeness Portfolio  (1)
Introduces SAHP goals for graduates.  Students demonstrate progression toward wholeness, compassion, support of diversity, appreciation of human worth, and commitment to lifelong personal and professional growth.

AHCJ 418  Physiology I (4)
Physiology of the human body, including cellular, neuromuscular, cardiovascular, respiratory, gastrointestinal, renal, and endocrine physiology.

CLSM 303 Urine and Body Fluid Analysis (1)
Urinalysis screening procedure and its application in the diagnosis of renal, systemic, and metabolic diseases. Analysis and morphology of body fluids. Lecture and laboratory.

CLSM 307 Medical Parasitology (3)
Medically important parasites: life cycles, clinical features, infective diagnostic stages. Demonstrations, slide studies and diagnostic procedures. Lecture and laboratory.

CLSM 309 Quantitative Analysis, Chemical (4)
To provide a rigorous background in those chemical principles that are particularly important to analytical clinical chemistry. The course will develop an appreciation for the task of judging the accuracy and precision of experimental data and the application of statistical methods. Both fundamental and practical aspects of chemical analysis are covered; neutralization titrations; acid-base titration; Spectrophotometric methods; and electrochemical and chromatographic methodologies. Lecture and Laboratory.

CLSM 321 Hematology I (4)
Examination of normal hematologic physiology, cellular development, and hemostasis in the human. Introduction to pathophysiology, with emphasis on clinical and laboratory evaluation of hematologic status. Theory and background of laboratory procedures used in diagnosis and treatment of hematologic and other diseases. Stress on proficiency in evaluation of normal and abnormal cellular morphology. Lecture and laboratory.

CLSM 322 Hematology II (4)
Theory and background of routine and special laboratory procedures used in diagnosis and treatment of hematologic and other diseases. Emphasis on peripheral blood-cell morphology, hematopoiesis, maturation, and kinetics. Pathophysiology of hematologic malignancies. Correlation of hemostasis testing with clinical hemostatic disorders. Lecture and laboratory.
Prerequisite: CLSM 321

CLSM 325 Clinical Immunology (3)
Presents the basic principles of immunology, Topics covered include humoral and cell-mediated immunity, complement, autoimmunity, immunodeficiency, hypersensitivity, tumor immunology, transplant immunology, virology, syphillis serology, and immunologic laboratory techniques.  Emphasizes principles, laboratory procedures and clinical significance.  Lecture and laboratory.

CLSM 327 Clinical and Pathogenic Microbiology I (5)
Introduction to microbiological concepts, leading to an in-depth study of the major groups of pathogenic bacteria and their relationship to human disease. Emphasis on clinical-laboratory identification methods and procedures. Lecture and laboratory.

CLSM 328 Clinical and Pathogenic Microbiology II (5)
Nature and control of microorganisms encountered in clinical material and various anatomical site., and their relationship to human disease. Emphasis on antimicrobial agents, mycology, and virology including hepatic viruses and HIV/AIDS. Lecture and laboratory.
Prerequisite: CLSM 327 or consent of instructor

CLSM 331 Biochemistry (5)
Chemical structure and metabolism of carbohydrates, amino acids, lipids, and nucleic acids. Protein synthesis, functions, and analysis. Enzymes and their structure, function, kinetics, and regulation. Lecture and laboratory.

CLSM 332 Clinical Chemistry I (4)
Clinical chemistry procedures and their clinical significance in medicine, with focus on the following areas: carbohydrates and diabetes mellitus, proteins, lipids, lipoproteins, cardiovascular disease, enzymes, liver function, iron, hemoglobin, and porphyrins. Quality assurance, method evaluation, and establishment of reference ranges. Lecture and laboratory.
Prerequisite: CLSM 331 or consent of instructor.

CLSM 333 Clinical Chemistry II (4)
Clinical chemistry procedures and their clinical significance in medicine, with focus on the following areas: fluids and electrolytes, acid-base balance, the endocrine system; thyroid, parathyroid, adrenal cortex and catecholamines, and steroids; reproduction, pregnancy, and fetal well-being; therapeutic drug monitoring and toxicology. Lecture and laboratory.

CLSM 341 Immunohematology I (3)
Fundamentals of antigen-antibody reactions. Study of major blood-group systems, compatibility testing, and antibody-identification techniques. Clinical analysis of hemolytic disease of the newborn. Lecture and laboratory.

CLSM 342 Immunohematology II (3)
Blood collection, donor testing, component preparation, and quality management in the collection facility. Identification of multiple antibodies, typing discrepancies, hemotherapy, hazards of transfusion, and investigation of autoimmune hemolytic disease. Lecture and laboratory.
Prerequisite: CLSM 341

CLSM 396 Junior Seminar

Senior year didactics

POST-SUMMER (5 weeks) AUTUMN WINTER SPRING
Clinical practicum begins

(See the clinical coordinator for schedule.)

CLSM 451
Laboratory Management I

(2)

CLSM 452
Laboratory Management II

(2)

CLSM 453
Laboratory Management III

(2)

CLSM 435
Immunoassay & Molecular Diagnostic Techniques

(3)

CLSM 496
CLSM Seminar I

(1)

CLSM 497
CLS Seminar II

(1)

CLSM 498
CLS Seminar III

(2)

. AHCJ 498
Portfolio Practicum II

(1)

AHCJ 498
Portfolio Practicum II

(cont.)

AHCJ 498
Portfolio Practicum II

(cont.)

. . REL_ ___
Religious studies

(2)

REL_ ___
Religious studies

(2)

Total units: 1-5 + Practicum (1-5) + Practicum (1-5)+ Practicum (1-5) + Practicum

Senior year clinical practicum

CLSM 471 Clinical Practicum I * (1-5 Units)
Corequisites: CLSM 422 Hematology III (1-5), CLSM 411 Urine & Body Fluid Analysis II (1)

CLSM 472 Clinical Practicum II **(1-5 Units)
Corequisites: CLSM 413 Diagnostic Microbiology (1-7), CLSM 442 Immunohematology III (1-2)

CLSM 473 Clinical Practicum III *** (1-5 Units)
Corequisites: CLSM 434 Clinical Chemistry III (1-4), CLSM 455 Special Procedures (1-3)

Total units for senior clinical practicum:
* Clinical Practicum I is a 12-week clinical rotation in the areas of Hematology, Urinalysis & Parasitology.
**Clinical Practicum II is a 12-week clinical rotation in the areas of microbiology and immunohematology.
***Clinical Practicum III is a 12-week clinical rotation in the areas of chemistry, immunology, and special procedures.

The three courses will be registered for through block registration and be taken successively.

Course descriptions - senior year

CLSM 411 Urine and Body Fluid Analysis II (1) Correlation and application of theory and clinical experience with analytical techniques. Assessment and interpretation of data. Evaluation and comparison of methodologies. Urinalysis screening procedures and applications in the diagnosis of renal, systemic, and metabolic diseases. Processing, analysis, and morphologic evaluation of body fluids.
Prerequisite: CLSM 303

CLSM 413 Diagnostic Microbiology II (1 to 7)
Correlation and application of theory and clinical experience with analytical techniques. Assessment and interpretation of data. Evaluation and comparison of methodologies. Directed study and review of diagnostic bacteriology, mycology, parasitology, and virology. Emphasis on isolation and identification of pathogenic microorganisms. Susceptibility testing, instrumentation, and rapid identification methods included. Course will be completed over 2 quarters.
Prerequisite: CLSM 307, 327, 328.

CLSM 422 Hematology III (1-5)
Correlation and application of theory and clinical experience with analytical techniques. Assessment and interpretation of data. Evaluation and comparison of methodologies. Directed study and review of hemostasis, cellular quantification and identification techniques, and clinical hematology. Includes white-cell, red-cell, platelet, and hemostatic disorders. Course will be completed over 2 quarters.
Prerequisite: CLSM 321, 322.

CLSM 434 Clinical chemistry III (1-4)
Correlation and application of theory and clinical experience with analytical techniques. Assessment and interpretation of data. Evaluation and comparison of methodologies. Directed study and review of include: carbohydrates, proteins, lipids, enzymology, electrolytes, acid-base balance, endocrine system, and therapeutic drug monitoring. Course will be completed over 2 quarters.
Prerequisite: CLSM 333.

CLSM 435 Immunoassay & Molecular Diagnostic Techniques (3)
Reviews common immuoassay methodologies and discusses molecular diagnostic techniques, including fluorescent in Situ hybridization (FISH); as well as Northern, Southern and Western immunoblots.  Compares different signal and target amplification methodologies.  Discusses and applies the foregoing methods to clinical laboratory science.

CLSM 442 Immunohematology III (1-2)
Application of theory and techniques routinely used in transfusion medicine. Emphasis on correlation with clinical experience. Directed study and review include: type and screen, antibody identification, investigation of hemolytic disease of the newborn, hemotherapy, and hazards of transfusion. Assessment and interpretation of data. Overview of donor facilities: donor criteria, records management, component preparation, blood storage, and infectious disease testing. Course will be completed over 2 quarters.
Prerequisite: CLSM 341, 342.

CLSM 451 Clinical Laboratory Management I (2)
Introduction to management theory, including: management styles, professional communications, business ethics, group theory, team building, process management, process control, and personnel.

CLSM 452 Clinical Laboratory Management II (2)
Financial management, with emphasis on concepts, tools, and strategies underlying financial decision making. Topics include health care reimbursement systems, coding, billing, development of operating budgets, and financial reports. Concepts of financial negotiations, inventory management, and financial planning. Integration and application of analytical techniques used in the service industries.

CLSM 453 Clinical Laboratory Management III (2)
Introduction to theories of quality management, organization, strategic planning, and the decision making process. Review and analysis of government agencies, legislation, and regulatory bodies that impact laboratory management. Comparison of quality systems-management philosophies.

CLSM 455 Special Procedures (1-3)
Correlation and application of theory and clinical experience requiring assessment and interpretation of data. Evaluation and comparison of methodologies. Directed study and review include the following immunoassays: chemiluminescence, enzyme and radioisotopic assays, microparticle enzyme immunoassay, and fluorescence polarization and nephelometry. Also includes: thin-layer and high-pressure liquid chromatography, electrophoresis, spectrophotometry, toxicology, amino acids, rapid detection testing for bacteria and viruses, polymerase and ligase chain reactions, Western blot assays, serology and current immunologic techniques. Course will be completed over 2 quarters
Prerequisite: CLSM 324, 333.

CLSM 471 Clinical Practicum I (1-5)
Twelve weeks of supervised clinical laboratory experience in selected areas, including: parasitology, hematology, urinalysis, and body fluids. Student performs tests routinely done in these areas of the clinical laboratory. Selected case studies included as part of floor rounds. Course will be completed over 2 quarters.
Prerequisite: Satisfactory completion of Clinical Laboratory Science Program junior-year courses.

CLSM 472 Clinical Practicum II (1-5)
Twelve weeks of supervised clinical laboratory experience in selected areas, including: microbiology and immunohematology, with experience in transfusion services and in a blood-collection facility. Student performs tests routinely done in these areas of the clinical laboratory. Special emphasis on clinical laboratory quality-control procedures and evaluation. Course will be completed over 2 quarters.
Prerequisite: Satisfactory completion of Clinical Laboratory Science Program junior-year courses.

CLSM 473 Clinical Practicum III (1-5)
Twelve weeks of supervised clinical laboratory experience in selected areas, including: chemistry and special procedures. Student performs test routinely done in these areas of the clinical laboratory. Incorporates experience in administrative duties. Course will be completed over 2 quarters.
Prerequisite: Satisfactory completion of Clinical Laboratory Science Program junior-year courses.

CLSM 496 Clinical Laboratory Science Seminar I (1)
Introduction to an assigned capstone project, designed to incorporate skills developed and knowledge obtained in the Clinical Laboratory Science Program junior year. Project must be of current interest to the laboratory field. Topics related to the project include literature-search methods, research methods, presentation skills, team building, assessment of impact on clinical outcomes, and analysis and implementation of clinical applications.
Prerequisite: Satisfactory completion of CLS program junior- year courses or consent of instructor.

CLSM 497 Clinical Laboratory Science Seminar II (1)
Continuation of assigned capstone project. Presentation of relevant con temporary topics.
Prerequisite: CLSM 496 or consent of instructor.

CLSM 498 Clinical Laboratory Science Seminar III (2)
Students meet regularly with faculty advisers to formulate plans and provide status reports on progress of capstone project. Additional time outside regular class periods. Submission and presentation of assigned capstone to faculty as a culminating activity.
Prerequisite: CLSM 496, 497; or consent of instructor

Academic progression

A minimum grade of C (2.0) is required for all courses in the program. A grade of less than C in any one course, or unsatisfactory clinical performance, will be cause for dismissal from the program for the remaining academic year. Readmission to the program will require reapplication.

Professional registration

Completion of the required sequence of academic coursework and directed professional experience prepares the graduate to take the certifying examination of the ASCP Board of Certification and be eligible for licensure in the State of California. Information regarding examinations can be obtained by the following websites:  www.ascp.org and www.cdph.ca.gov/LFS